Fumonisin B1 ( ——— )

产品货号. M38015 CAS No. 116355-83-0

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Fumonisin B1
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Fumonisin B1 is a mycotoxin produced from Fusarium moniliforme. Fumonisin B1 is a potent inhibitor of sphingosine N-acyltransferase (ceramide synthase) and disrupts de novo sphingolipid biosynthesis.Fumonisin B1 is the most abundant and toxic fumonisin.
产品描述

Fumonisin B1 is a mycotoxin produced from Fusarium moniliforme. Fumonisin B1 is a potent inhibitor of sphingosine N-acyltransferase (ceramide synthase) and disrupts de novo sphingolipid biosynthesis.Fumonisin B1 is the most abundant and toxic fumonisin.
体外实验

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体内实验

Fumonisin B1 改变猴肾细胞的基因表达和信号转导通路。 Fumonisin B1 增加鞘脂代谢的初始破坏和鞘氨醇在 LLC-PK1 肾细胞中的积累，引起大鼠星形胶质细胞凋亡型 DNA 损伤。
同义词

———
通路

Others
靶点

Other Targets
受体

Sphingosine N-acyltransferase
研究领域

———
适应症

———

CAS Number

116355-83-0
分子量

721.83
分子式

C34H59NO15
纯度

>98% (HPLC)
溶解度

H2O : 16.67 mg/mL (23.09 mM)
SMILES

O.CCCC[C@@H](C)[C@@H](OC(=O)C[C@@H](CC(O)=O)C(O)=O)C(C[C@@H](C)C[C@H](O)CCCC[C@@H](O)C[C@H](O)[C@H](C)N)OC(=O)C[C@@H](CC(O)=O)C(O)=O
化学全称

O.CCCC[C@@H](C)[C@@H](OC(=O)C[C@@H](CC(O)=O)C(O)=O)C(C[C@@H](C)C[C@H](O)CCCC[C@@H](O)C[C@H](O)[C@H](C)N)OC(=O)C[C@@H](CC(O)=O)C(O)=O

1. Henry MH, et al. The toxicity of fumonisin B1, B2, and B3, individually and in combination, in chicken embryos. Poult Sci. 2001 Apr;80(4):401-7.?

计算器

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